Molecular weight and structure of 7 S nerve growth factor protein.
نویسندگان
چکیده
منابع مشابه
Molecular weight and structure of 7 S nerve growth factor protein.
The molecular weight of 7 S nerve growth factor has been studied in the analytical ultracentrifuge between pH values 6.8 and 7.8. At pH 6.8, where no dissociation is observed, the molecular weight was found to be 137,000 plus and minus 7,000. Between pH values 7.4 and 7.8 there is some dissociation. Using the data from this study and results in the literature, a model of 7 S nerve growth factor...
متن کاملMolecular Weight and Structure of 7 S Nerve Growth Factor Protein
The molecular weight of 7 S nerve growth factor has been studied in the analytical ultracentrifuge between pH values 6.8 and 7.8. At pH 6.8, where no dissociation is observed, the molecular weight was found to be 137,000 f 7,000. Between pH values 7.4 and 7.8 there is some dissociation. Using the data from this study and results in the literature, a model of 7 S nerve growth factor, (c&)~, in r...
متن کاملSubunit Interactions of 7 S Nerve Growth Factor ? - ESTERASE ACTIVITY
The y-esterase activity of 7 S nerve growth factor (NGF) is depressed relative to free subunit because of constraints within the oligomer. 4 M urea causes a reversible dissociation of 7 S NGF and concomitant increase in esterase activity. The y-esterase activity with tosyl-arginyl-methyl-ester increased between 1 and 4 M urea and was inhibited at higher concentrations. Upon dilution of 7 S NGF ...
متن کاملRegulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor
PC12 rat pheochromocytoma cells respond to nerve growth factor (NGF) protein by shifting from a chromaffin-cell-like phenotype to a neurite-bearing sympathetic-neuron-like phenotype. Comparison of the phosphoprotein patterns of the cells by SDS PAGE after various times of NGF treatment revealed a high molecular weight (Mr greater than or approximately 300,000) band whose relative intensity prog...
متن کاملCerebrospinal fluid nerve growth factor and total protein concentration in the children with meningitis
Meningitis is one of the most common infectious cerebral nervous system (CNS), defined as an inflammation of the meninges. It is clinically categorized into a chronic and acute based on the acuity of symptoms. Vomiting, bulging fontanel and fever are the main symptoms in the patients with meningitis. Bacterial meningitis is a severe, potentially life-threatening infection that is associated wit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1975
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)41752-3